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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223714Generated: October 27, 2026

4-Amino-2-methylquinoline → 1-(3-Chloro-propyl)-3-(2-methyl-quinolin-4-yl)-urea

https://huagongshe.com/reaction/2223714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-methylquinolineHCID 81116—
ReactantPropane, 1-chloro-3-isocyanato-HCID 166752—
Reactant1-(2-Chloroethyl)-3-(2-methylquinolin-4-yl)ureaHCID 2344366—
Product1-(3-Chloro-propyl)-3-(2-methyl-quinolin-4-yl)-ureaHCID 22643333—

Reaction Steps

The title compound is prepared from 4-amino-2-methylquinoline and 3-chloropropylisocyanate by the method used in the preparation of Example 1A, 1-(2-chloroethyl)-3-(2-methyl-quinol-4-yl)-urea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375227B2
Source datasetuspto-grants-2008_05
ORD IDord-b1407bc43b3649fb81cf498fb676d190
Source noteuspto-grants-2008_05