HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyl-4-piperidinol → 1-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-propyl]-3-(2-methyl-quinolin-4-yl)-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyl-4-piperidinol | HCID 98152 | — |
| Reactant | 1-[2-(4-Hydroxy-4-p-tolyl-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea | HCID 17956568 | — |
| Reactant | 1-(3-Chloro-propyl)-3-(2-methyl-quinolin-4-yl)-urea | HCID 22643333 | — |
| Product | 1-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-propyl]-3-(2-methyl-quinolin-4-yl)-urea | HCID 17956457 | — |
Reaction Steps
Prepared from 4-hydroxy-4-benzyl-piperidine and 1-(3-chloro-propyl)-3-(2-methyl-quinolin-4-yl)-urea using the method exemplified with Example 341, 1-[2-(4-hydroxy-4-p-tolyl-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07375227B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-de6fdda66ab043ff9654ba153705c07e |
| Source note | uspto-grants-2008_05 |