HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 59715913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59715933 | HCID 59715933 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59715913 | HCID 59715913 | — |
Reaction Steps
A suspension of 1-{2-[4-(3-methyl-benzylidene)-piperidin-1-yl]-ethyl}-3-(2-methyl-quinolin-4-yl)-urea (21 mg, 0.05 mmol), 2M aqueous HCl (0.5 mL, 1 mmol) and Pd—C (10%, 5 mg) in MeOH (2 mL) is stirred under hydrogen atmosphere for 6 h. The catalyst is filtered off and the filtrate evaporated to provide the title compound as hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07375227B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-a9e1c22a8de641168f12936e74df0aa9 |
| Source note | uspto-grants-2008_05 |