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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223728Generated: October 30, 2026

Hydrochloric Acid → HCID 59715913, compound

https://huagongshe.com/reaction/2223728

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 59715933HCID 59715933—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 59715913HCID 59715913—

Reaction Steps

A suspension of 1-{2-[4-(3-methyl-benzylidene)-piperidin-1-yl]-ethyl}-3-(2-methyl-quinolin-4-yl)-urea (21 mg, 0.05 mmol), 2M aqueous HCl (0.5 mL, 1 mmol) and Pd—C (10%, 5 mg) in MeOH (2 mL) is stirred under hydrogen atmosphere for 6 h. The catalyst is filtered off and the filtrate evaporated to provide the title compound as hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07375227B2
Source datasetuspto-grants-2008_05
ORD IDord-a9e1c22a8de641168f12936e74df0aa9
Source noteuspto-grants-2008_05