HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2223737Generated: October 30, 2026
1-(2-Amino-ethyl)-4-benzyl-piperidine-4-carboxylic acid ethyl ester → 1-(2-Amino-ethyl)-4-benzyl-piperidine-4-carboxylic acid
https://huagongshe.com/reaction/2223737
Participants
| Role | Name | HCID | Charge |
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| Reactant | 1-(2-Amino-ethyl)-4-benzyl-piperidine-4-carboxylic acid ethyl ester | HCID 59715921 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 1-(2-Amino-ethyl)-4-benzyl-piperidine-4-carboxylic acid | HCID 17956596 | — |
Reaction Steps
1-(2-Amino-ethyl)-4-benzyl-piperidine-4-carboxylic acid ethyl ester (2.5 g, 10 mmol) is dissolved in 6N aqueous HCl (40 mL) and the mixture heated at 90° C. for 96 h. The reaction mixture is evaporated to provide the title compound as hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07375227B2 |
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| Source dataset | uspto-grants-2008_05 |
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| ORD ID | ord-d2c8692158c64358a6ab7f4131cc321b |
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| Source note | uspto-grants-2008_05 |
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