Acetic Anhydride → HCID 23021166, compound

HRID 2223846Notes

Reaction equation

HRID 2223846 reaction equation
[CH2:1]([Si:3]([CH2:18][CH3:19])([CH2:16][CH3:17])[O:4][CH2:5][C:6]1([CH2:12][CH2:13][CH2:14][OH:15])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH3:2].[C:20](OC(=O)C)(=[O:22])[CH3:21]>N1C=CC=CC=1>[C:20]([O:15][CH2:14][CH2:13][CH2:12][C:6]1([CH2:5][O:4][Si:3]([CH2:1][CH3:2])([CH2:16][CH3:17])[CH2:18][CH3:19])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)(=[O:22])[CH3:21]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 69146728HCID 69146728, compound

Product 1

HCID 23021166HCID 23021166, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To 3-[1-(triethylsiloxymethyl)cyclohexyl]propan-1-ol (410 mg) were added acetic anhydride (3 mL) and pyridine (3 mL) at room temperature. The solution was stirred at room temperature for 2 hours and concentrated under reduced pressure. The residue was distilled with toluene azeotropically to give the title compound (480 mg). This product was subjected to the subsequent step without further pirification.

Workup

  1. concentrationconcentrated under reduced pressure
  2. distillationThe residue was distilled with toluene azeotropically

Sources & evidence

ORD record
ord-ad1c004b4ad64b9dbee220f641035eec
Source dataset
uspto-grants-2008_05
Patent number
US07375115B2

Reaction notes

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