Acetic Anhydride → HCID 59714905, compound

HRID 2223866Notes

Reaction equation

HRID 2223866 reaction equation
[O:1]([CH2:19][CH2:20][C:21]1([CH2:27][CH2:28][C:29]([CH2:35][OH:36])([CH2:32][CH2:33][OH:34])[CH2:30][OH:31])[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1)[Si:2]([C:15]([CH3:18])([CH3:17])[CH3:16])([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(O[C:41](=[O:43])[CH3:42])(=O)C>N1C=CC=CC=1>[C:19]([O:31][CH2:30][C:29]([CH2:28][CH2:27][C:21]1([CH2:20][CH2:19][O:1][Si:2]([C:15]([CH3:17])([CH3:18])[CH3:16])([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1)([CH2:32][CH2:33][O:34][C:41](=[O:43])[CH3:42])[CH2:35][O:36][C:30](=[O:31])[CH3:29])(=[O:1])[CH3:20]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 59714981HCID 59714981, compound

Product 1

HCID 59714905HCID 59714905, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a solution of 2-[2-[1-[2-(tert-butyldiphenylsiloxy)ethyl]cyclohexyl]ethyl]-2-hydroxymethylbutan-1,4-diol (300 mg) in pyridine (5.0 mL) was added acetic anhydride (5.0 mL) at room temperature. After stirring the solution at room temperature for 16 hours, it was concentrated under reduced pressure to give the title compound (340 mg).

Workup

  1. concentrationit was concentrated under reduced pressure

Sources & evidence

ORD record
ord-e70ef739c7ab48bf983e4c33855f8c5a
Source dataset
uspto-grants-2008_05
Patent number
US07375115B2

Reaction notes

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