HCID 10118758, compound → HCID 10180311, compound

Participants

Reaction Steps

To a solution of tert-butyl [2-[3-[4-[N-(5-metylpyridin-2-yl)-2-furancarboxamido]piperidin-1-yl]propyl]phenyl]carbamate (790 mg) in methanol (15 mL) was added a 4N hydrochloric acid/ethyl acetate solution (2.3 mL) at room temperature. The solution was stirred at room temperature for 16 hours. The solution was then concentrated under reduced pressure. Saturated aqueous sodium bicarbonate solution was added to the residue and the solution was extracted with chloroform. The extract was dried over over anhydrous sodium sulfate, and then, concentrated under reduced pressure to give the title compound (700 mg).

Provenance & Evidence