HCID 58641524, compound → HCID 68434769, compound

HRID 2224075Notes

Reaction equation

HRID 2224075 reaction equation
[C:1]1([S:7]([C:10]2[CH:27]=[CH:26][C:13]3[N:14]([C:18](=O)[CH2:19][N:20]4[CH:24]=[CH:23][N:22]=[CH:21]4)[CH2:15][CH2:16][O:17][C:12]=3[CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C1COCC1>[C:1]1([S:7]([C:10]2[CH:27]=[CH:26][C:13]3[N:14]([CH2:18][CH2:19][N:20]4[CH:24]=[CH:23][NH:22][CH2:21]4)[CH2:15][CH2:16][O:17][C:12]=3[CH:11]=2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 1

HCID 58641524HCID 58641524, compound

Product 1

HCID 68434769HCID 68434769, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

7-Benzenesulfonyl-4-[2-(3H-imidazol-1-yl)-ethyl]-3,4-dihydro-2H-benzo[1,4]oxazine was prepared by reducing 1-(7-benzenesulfonyl-2,3-dihydro-benzo[1,4]oxazin-4-yl)-2-imidazol-1-yl-ethanone with BH3:THF using the procedure of Example 9. mp: 61.5-64.4° C.

Sources & evidence

ORD record
ord-cdb04d856e66474e82e2ac257e13c2c9
Source dataset
uspto-grants-2008_05
Patent number
US07378415B2

Reaction notes

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