HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Bromomethyl)-2-(trifluoromethyl)pyridine → 7-Chloro-8-(4-chlorophenyl)-2-(6-(trifluoromethyl)pyridin-3-yl)methyl-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Bromomethyl)-2-(trifluoromethyl)pyridine | HCID 14405125 | — |
| Reactant | 7-chloro-8-(4-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one | HCID 59716856 | — |
| Product | 7-Chloro-8-(4-chlorophenyl)-2-(6-(trifluoromethyl)pyridin-3-yl)methyl-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one | HCID 59716903 | — |
Reaction Steps
Using the procedure described in Example 274, 7-chloro-8-(4-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one prepared as described in Example 273 was reacted with 5-(bromomethyl)-2-(trifluoromethyl)pyridine to give the title compound, 7-chloro-8-(4-chlorophenyl)-2-(6-(trifluoromethyl)pyridin-3-yl)methyl-[1,2,4]triazolo[4,3-b]pyridazin-3 (2H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378418B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-35c77670b0cd44f4ba0e70207cb4a57a |
| Source note | uspto-grants-2008_05 |