1,1'-Carbonyldiimidazole → HCID 59716580, compound

HRID 2224265Notes

Reaction equation

HRID 2224265 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]([C:17]3[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=3)=[C:11]([NH:15][NH2:16])[N:12]=[N:13][CH:14]=2)=[CH:5][CH:4]=1.[C:23](N1C=CN=C1)(N1C=CN=C1)=[O:24]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:14]=[N:13][N:12]3[C:23](=[O:24])[NH:16][N:15]=[C:11]3[C:10]=2[C:17]2[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 682631,1'-CarbonyldiimidazoleHCID 59716688HCID 59716688, compound

Product 1

HCID 59716580HCID 59716580, compound

Procedure

The title compound was prepared by reacting 1-(5-(4-methoxyphenyl)-4-(pyridin-4-yl)pyridazin-3-yl)hydrazine with carbonyldiimidazole (CDI) by procedures analogous to those described in Example 279F to give 7-(4-methoxyphenyl)-8-(pyridine-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one. LC/MS (method A): RT=1.37 min, (M+H)+=320.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-fc1c2b3b794a435fb39a973578da3da7
Source dataset
uspto-grants-2008_05
Patent number
US07378418B2

Reaction notes

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