HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloronicotinic acid → (2-Chloropyridin-3-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloronicotinic acid | HCID 76258 | — |
| Reactant | (2,6-Dichloro-5-fluoropyridin-3-yl)methanol | HCID 23114857 | — |
| Product | (2-Chloropyridin-3-yl)methanol | HCID 2763647 | 44% |
Reaction Steps
Compound 12A (0.20 g, 44%) was prepared from 2-chloro-nicotinic acid (0.5 g, 3.17 mmol) using a procedure similar to the synthesis of 1A. HPLC Rt=0.77 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-04544bfbaa804f76a00282c19520cb99 |
| Source note | uspto-grants-2008_05 |