HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,6-Dichloro-5-fluoropyridin-3-yl)methanol → (3-Iodopyridin-4-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,6-Dichloro-5-fluoropyridin-3-yl)methanol | HCID 23114857 | — |
| Reactant | 3-Iodo-isonicotinic acid hydrochloride | HCID 68978020 | — |
| Product | (3-Iodopyridin-4-yl)methanol | HCID 23106621 | 33% |
Reaction Steps
Compound 24A (142 mg, 33%) was prepared from 3-iodo-isonicotinic acid hydrochloride (522 mg, 1.83 mmol) ) using a procedure similar to the synthesis of 1A. HPLC Rt=0.34 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-b36966b807584a1eb391bd21a898a2e5 |
| Source note | uspto-grants-2008_05 |