HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,6-Dichloro-5-fluoropyridin-3-yl)methanol → (2-Chloro-5-iodo-pyridin-4-yl)-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,6-Dichloro-5-fluoropyridin-3-yl)methanol | HCID 23114857 | — |
| Reactant | 2-Chloro-5-iodo-isonicotinic acid | HCID 59717568 | — |
| Product | (2-Chloro-5-iodo-pyridin-4-yl)-methanol | HCID 59717559 | 51.3% |
Reaction Steps
Compound 25C (0.38 g, 51%) was prepared from 25B (0.78 g, 2.75 mmol) using a procedure similar to the synthesis of 1A. HPLC Rt=1.74 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-ffa05fc280f543b3a27f10d80d3b9fe6 |
| Source note | uspto-grants-2008_05 |