Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2224338Generated: October 31, 2026

2,4-Dichloro-5-(chloromethyl)pyridine → N-(4,6-dichloro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide

https://huagongshe.com/reaction/2224338

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dichloro-5-(chloromethyl)pyridineHCID 2762728—
ReactantN-(2,6-dichloro-5-fluoro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamideHCID 59717570—
ProductN-(4,6-dichloro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamideHCID 5971760082%

Reaction Steps

Compound 41C (210 mg, 82%) was prepared from 41B (157 mg, 0.8 mmol) and bb (129 mg, 0.8 mmol) using a procedure similar to the synthesis of 1C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07378426B2
Source datasetuspto-grants-2008_05
ORD IDord-01d1c66d3ffc4873ae36f92b1e6baa77
Source noteuspto-grants-2008_05