HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloro-5-(chloromethyl)pyridine → N-(4,6-dichloro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloro-5-(chloromethyl)pyridine | HCID 2762728 | — |
| Reactant | N-(2,6-dichloro-5-fluoro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide | HCID 59717570 | — |
| Product | N-(4,6-dichloro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide | HCID 59717600 | 82% |
Reaction Steps
Compound 41C (210 mg, 82%) was prepared from 41B (157 mg, 0.8 mmol) and bb (129 mg, 0.8 mmol) using a procedure similar to the synthesis of 1C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-01d1c66d3ffc4873ae36f92b1e6baa77 |
| Source note | uspto-grants-2008_05 |