HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4,6-dichloro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide → 1-(3-chloro-12H-2,11-diaza-dibenzo[a,e]cycloocten-11-yl)-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4,6-dichloro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide | HCID 59717600 | — |
| Reactant | 6-Acetyl-2-chloro-3-fluoro-5,6-dihydro-pyrido[3,2-c][1]benzazocine | HCID 74393412 | — |
| Product | 1-(3-chloro-12H-2,11-diaza-dibenzo[a,e]cycloocten-11-yl)-ethanone | HCID 72366777 | 63.2% |
Reaction Steps
Compound 41D (117 mg, 63%) was prepared from 41C (210 mg, 0.65 mmol) using a procedure similar to the synthesis of 1D. HPLC Rt=2.519 min; LCMS Found: (M+H)+=285.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-fe97389afd714fc6b5822833d3da90e2 |
| Source note | uspto-grants-2008_05 |