HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-3-(bromomethyl)-2-chloropyridine → N-(5-Bromo-2-chloro-pyridin-3-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-3-(bromomethyl)-2-chloropyridine | HCID 59717550 | — |
| Reactant | N-(2,6-dichloro-5-fluoro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide | HCID 59717570 | — |
| Reactant | N-(4-chloro-2-vinyl-phenyl)-acetamide | HCID 59717611 | — |
| Product | N-(5-Bromo-2-chloro-pyridin-3-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide | HCID 59717599 | 94% |
Reaction Steps
Compound 76C (0.19 g, 94%) was prepared from 76B (0.145 g, 0.51 mmol) and 9B (0.1 mg, 0.51 mmol) using a procedure similar to the synthesis of 1C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-5f19775437bb4781824a2d24b51e0585 |
| Source note | uspto-grants-2008_05 |