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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2224362Generated: October 31, 2026

5-Bromo-3-(bromomethyl)-2-chloropyridine → N-(5-Bromo-2-chloro-pyridin-3-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide

https://huagongshe.com/reaction/2224362

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-3-(bromomethyl)-2-chloropyridineHCID 59717550—
ReactantN-(2,6-dichloro-5-fluoro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamideHCID 59717570—
ReactantN-(4-chloro-2-vinyl-phenyl)-acetamideHCID 59717611—
ProductN-(5-Bromo-2-chloro-pyridin-3-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamideHCID 5971759994%

Reaction Steps

Compound 76C (0.19 g, 94%) was prepared from 76B (0.145 g, 0.51 mmol) and 9B (0.1 mg, 0.51 mmol) using a procedure similar to the synthesis of 1C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07378426B2
Source datasetuspto-grants-2008_05
ORD IDord-5f19775437bb4781824a2d24b51e0585
Source noteuspto-grants-2008_05