HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromomethyl-2-chloro-5-iodo-pyridine → N-(2-Chloro-5-iodo-pyridin-4-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromomethyl-2-chloro-5-iodo-pyridine | HCID 59717563 | — |
| Reactant | N-(2,6-dichloro-5-fluoro-pyridin-3-ylmethyl)-N-(2-vinyl-phenyl)-acetamide | HCID 59717570 | — |
| Reactant | N-(5-Bromo-2-chloro-pyridin-3-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide | HCID 59717599 | — |
| Product | N-(2-Chloro-5-iodo-pyridin-4-ylmethyl)-N-(4-chloro-2-vinyl-phenyl)-acetamide | HCID 59717576 | — |
Reaction Steps
Compound 77B was prepared from 77A (0.75 mg, 0.22 mmol) and 76C (0.44 g, 0.22 mmol) using a procedure similar to the synthesis of 1C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07378426B2 |
| Source dataset | uspto-grants-2008_05 |
| ORD ID | ord-bd5c6546150240fd97a069bc90d5837e |
| Source note | uspto-grants-2008_05 |