Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2224489Generated: October 30, 2026

Ethanol, 2-[(3-aminophenyl)sulfonyl]- → HCID 11512019, compound

https://huagongshe.com/reaction/2224489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanol, 2-[(3-aminophenyl)sulfonyl]-HCID 78905—
Reactant(3-Nitrophenyl)methanesulfonyl chlorideHCID 13196775—
Reactant7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acidHCID 66650268—
ProductHCID 11512019HCID 11512019—

Reaction Steps

The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C.1) and 3-(2-hydroxy-ethanesulfonyl)-aniline [CAS-Nr. 344750-15-8; prepared from commercially available 3-nitro-phenylmethane-sulfonyl chloride] according to general procedure II. Yellow solid. MS (ISP) 524.0 [(M−H)−]; mp 280° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07378417B2
Source datasetuspto-grants-2008_05
ORD IDord-771d53e6c4924c6ca2a3b64556aecf3c
Source noteuspto-grants-2008_05