Hydrogen chloride-ethyl acetate → HCID 68920400, compound

HRID 2224647Notes

Reaction equation

HRID 2224647 reaction equation
[N+:1]([O:4][CH2:5][C:6]1[N:11]=[C:10]([CH3:12])[C:9]([O:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][C:22](=[O:24])[CH3:23])=[CH:8][CH:7]=1)([O-:3])=[O:2].C(OCC)(=O)C.[ClH:32]>C(OCC)(=O)C>[ClH:32].[N+:1]([O:4][CH2:5][C:6]1[N:11]=[C:10]([CH3:12])[C:9]([O:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:21][C:22](=[O:24])[CH3:23])=[CH:8][CH:7]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 68920401HCID 68920401, compound

Product 1

HCID 68920400HCID 68920400, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To a solution of 2-acetyloxybenzoic acid 6-(nitrooxymethyl)-2-methylpyridinyl ester (1 g, 2.88 mmoles) in ethyl acetate (20 ml) cooled at 0° C., a solution of ethyl acetate/HCl 5M is added by dropping under stirring. It is left for 1 hour at 0° C., then the temperature is let reach the room values. The formed precipitate is filtered and washed with ethyl ether. 900 mg of a solid product are obtained.

Workup

  1. filtrationThe formed precipitate is filtered
  2. washwashed with ethyl ether

Sources & evidence

ORD record
ord-300386353102411daacb7ba7410c269f
Source dataset
uspto-grants-2008_05
Patent number
US07378437B2

Reaction notes

Loading…