Cyclohexylamine → HCID 24319741, compound

HRID 2225121Notes

Reaction equation

HRID 2225121 reaction equation
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([S:12](Cl)(=[O:14])=[O:13])=[CH:4][CH:3]=1.[CH:16]1([NH2:22])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1.C(N(CC)CC)C>C(Cl)Cl>[CH:16]1([NH:22][S:12]([C:5]2[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[C:2]([CH3:1])=[CH:3][CH:4]=2)(=[O:14])=[O:13])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

5

Reactant 3

HCID 7965CyclohexylamineHCID 8471TriethylamineHCID 28007604-methylnaphthalene-1-sulfonyl Chloride

Product 1

HCID 24319741HCID 24319741, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 4-methyl-naphthalene -1-sulfonyl chloride (2.4 g, 10.0 mmol) in CH2Cl2 (30 mL), was added cyclohexylamine (1.4 g, 11.0 mmol) and triethylamine (2.8 mL, 20.0 mmol) and the resultant solution was stirred at room temperature overnight.

Sources & evidence

ORD record
ord-82d0f230c16048af9dcbbcce54cb5518
Source dataset
uspto-grants-2008_05
Patent number
US07378525B2

Reaction notes

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