Potassium Acetate → HCID 908666, compound

HRID 2225330Notes

Reaction equation

HRID 2225330 reaction equation
Cl[CH2:2][C:3]1[C:4](=[O:15])[NH:5][C:6]2[C:11]([CH:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2.[C:16]([O-:19])(=[O:18])[CH3:17].[K+]>C(OC(=O)C)(=O)C>[C:16]([O:19][CH2:2][C:3]1[C:4](=[O:15])[NH:5][C:6]2[C:11]([CH:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2)(=[O:18])[CH3:17]

Participants

4

Reactant 2

HCID 517044Potassium AcetateHCID 190038963-(Chloromethyl)-6-methoxyquinolin-2(1H)-one

Product 1

HCID 908666HCID 908666, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

2.2 Grams of 3-chloromethyl-6-methoxycarbostyril was dissolved in 20 ml of acetic anhydride, then 12 g of potassium acetate was added thereto and stirred at 60°-70° C. for 3 hours. The reaction mixture was poured in an ice-water and the crystals precipitated were collected by filtration. Recrystallized from acetone to obtain 2 g of 3-acetoxymethyl-6-methoxycarbostyril in the form of colorless prism-like crystals.

Workup

  1. customthe crystals precipitated
  2. filtrationwere collected by filtration
  3. customRecrystallized from acetone

Sources & evidence

ORD record
ord-3d4a24e664d443b68dc126dd24aaa6c3
Source dataset
uspto-grants-1994_09
Patent number
USRE034722

Reaction notes

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