HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylcyclohexylamine Hydrochloride → N-(4-methylcyclohexyl)-4-acetoxy-3-methoxycinnamamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylcyclohexylamine Hydrochloride | HCID 12714125 | — |
| Reactant | 4-Acetoxy-3-methoxycinnamoyl chloride | HCID 54468022 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(4-methylcyclohexyl)-4-acetoxy-3-methoxycinnamamide | HCID 54149475 | 65.3% |
Reaction Steps
Using 5.09 g of 4-acetoxy-3-methoxycinnamoyl chloride, 2.98 g of 4-methylcyclohexylamine hydrochloride, and 100 ml of pyridine, a reaction similar to that conducted in Example 53 was carried out. As a result, 4.31 g of N-(4-methylcyclohexyl)-4-acetoxy-3-methoxycinnamamide was obtained as yellowish white crystal, which had the following physiochemical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344845 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-e63df6ef2bfa45a3a342f1ac852c67e6 |
| Source note | uspto-grants-1994_09 |