Potassium Carbonate → HCID 54256544, compound

HRID 2225514Notes

Reaction equation

HRID 2225514 reaction equation
[CH3:1][C:2]1([CH3:25])[CH2:7][CH2:6][CH:5]([NH:8][C:9](=[O:24])[C:10](OC(=O)C)=[CH:11][C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[CH:13]=2)[CH2:4][CH2:3]1.C(=O)([O-])[O-:27].[K+].[K+]>CO>[CH3:1][C:2]1([CH3:25])[CH2:7][CH2:6][CH:5]([NH:8][C:9](=[O:24])[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([OH:27])=[C:14]([O:18][CH3:19])[CH:13]=2)[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 67842301HCID 67842301, compound

Product 1

HCID 54256544HCID 54256544, compoundYield 93%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Using 8.99 g of N-(4,4-dimethylcyclohexyl)-acetoxy-3-methoxycinnamamide (Example 63), 100 ml of methanol, and 10 g of potassium carbonate, a reaction similar to that conducted in Example 54 was carried out. As a result, 7.34 g of N-(4,4-dimethylcyclohexyl)-4-hydroxy-3-methoxycinnamamide (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties:

Workup

  1. customa reaction similar to

Sources & evidence

ORD record
ord-6be7807dc34b4b98bb3559edb625ef8a
Source dataset
uspto-grants-1994_09
Patent number
US05344845

Reaction notes

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