1-Methylpiperazine → HCID 178490543, compound

Participants

Reaction Steps

Using 3.9 g of N-(trans-4-methylcyclohexyl)-4-(2-chloroethoxy)-3-methoxycinnamamide (Example 138) and 24 ml of 1-methylpiperazine, a reaction similar to that conducted in Example 142 was carried out. As a result, 2.24 g of N-(trans-4-methylcyclohexyl)-4-[2-(4-methylpiperazinyl)ethoxy]-3-methoxycinnamamide (a compound of the present invention) was obtained as light-brownish white crystal, which had the following physioche mical properties:

Provenance & Evidence