Potassium Hydroxide → HCID 178490527, compound

Participants

Reaction Steps

Using 1.6 g of N-(trans-4-methylcyclohexyl)-4-[3(ethoxycarbonyl)propoxy]-3-methoxycinnamamide (Example 174), 20 ml of 2 M aqueous potassium hydroxide solution, and 80 ml of methanol, a reaction similar to that conducted in Example 169 was carried out. As a result, 1.36 g of N-(trans-4-methylcyclohexyl)-4-(3-carboxypropoxy) -3-methoxycinnamamide (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties:

Provenance & Evidence