HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178490554, compound → HCID 178490555, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178490554 | HCID 178490554 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178490555 | HCID 178490555 | 59.8% |
Reaction Steps
Using 0.2 g of 1-{4-{2-[N-(trans-4methylcyclohexyl)carbamoyl]vinyl}-2-methoxyphenoxyacetyl}-4-piperidinopiperidine (Example 190), 0.01 g of 10% palladium-carbon, and 30 ml of methanol, a reaction similar to that conducted in Example 147 was carried out. As a result, 0.12 g of 1-{4-{2- [N-(trans-4-methylcyclohexyl) carbamoyl]ethyl}- 2-methoxyphenoxyacetyl}-4-piperidinopiperidine (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344845 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-d9d2f2e5c6c14ef0aabcfdde0419df71 |
| Source note | uspto-grants-1994_09 |