反应详情

A mixture of 4-[[3-(4-fluorophenyl)propyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (0.58 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided 0.55 g which solidified and was crystallized from diethyl etherhexane to give 0.43 g of colorless 4-[[3-(4-fluorophenyl)propyl]oxy]-alpha-oxobenzeneacetic acid, mp 77°-78° C.

1. additionwas treated as in Example 19
2. extractionExtraction
3. customprovided 0.55 g which
4. customwas crystallized from diethyl etherhexane