HCID 67757615, compound → HCID 19004398, compound

HRID 2225639Notes

Reaction equation

HRID 2225639 reaction equation
C[O:2][C:3](=[O:22])[C:4](=[O:21])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12]/[CH:13]=[CH:14]/[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:7][CH:6]=1>CO.[OH-].[Na+]>[O:21]=[C:4]([C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12]/[CH:13]=[CH:14]/[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:7][CH:6]=1)[C:3]([OH:22])=[O:2]

Participants

4

Reactant 1

HCID 67757615HCID 67757615, compound

Product 1

HCID 19004398HCID 19004398, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

A mixture of (E)-alpha-oxo-4- [(3-phenyl-2-propenyl)oxy]benzeneacetic acid methyl ester 0. 1 molar hydrate (0.7 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided solids which were crystallized from diethyl etherhexane to give 0.55 g of colorless (E)-alpha-oxo-4-[(3-phenyl-2-propenyl)oxy]benzeneacetic acid, mp 111°-112° C.

Workup

  1. extractionExtraction
  2. customprovided solids which
  3. customwere crystallized from diethyl etherhexane

Sources & evidence

ORD record
ord-c2bc2fa50b55408594704578115a5ed6
Source dataset
uspto-grants-1994_09
Patent number
US05344843

Reaction notes

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