HCID 54388349, compound → HCID 19004355, compound

Participants

Reaction Steps

A mixture of 4-[[2-(4-nitrophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (4:1) molar hydrate (0.65 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided 0.6 g of crude product which solidified and was crystallized from dichloromethane-hexane to give 0.55 g of colorless 4-[[2-(4nitrophenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid, mp 129°-130° C.

Provenance & Evidence