HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(methylsulfonyloxymethyl)piperidine-1-carboxylate → 4-[2-Fluoro-4-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenoxymethyl]-piperidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(methylsulfonyloxymethyl)piperidine-1-carboxylate | HCID 2765838 | — |
| Reactant | 2-Fluoro-4-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenol | HCID 66865246 | — |
| Product | 4-[2-Fluoro-4-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenoxymethyl]-piperidine-1-carboxylic acid tert-butyl ester | HCID 66864498 | — |
Reaction Steps
Prepared essentially as Preparation 2 (step 2) using 4-methanesulfonyloxymethyl-piperidine-1-carboxylic acid tert-butyl ester and 2-fluoro-4-(1-methanesulfonyl-1,2,3,6-tetrahydro-pyridin-4-yl)-phenol as starting materials. MS (m/z) 414 (M−55).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08207344B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-565b5ea5dd5d4963898d7ea3dcfd14a8 |
| Source note | uspto-grants-2012_06 |