Acetic Anhydride → Ether acetate

HRID 2225950Notes

Reaction equation

HRID 2225950 reaction equation
[O:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:6]([O:9]C(=O)C)(=[O:8])[CH3:7]>C(O)(=O)C>[CH3:3][CH2:2][O:1][CH2:5][CH3:4].[C:6]([O-:9])(=[O:8])[CH3:7]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 8028Tetrahydrofuran

Product 1

HCID 21226428Ether acetateYield 58.2%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
40 °C

Procedure

The obtained catalyst was pulverized into 20-40 mesh. 25 g of the pulverized catalyst was placed in a slurry reactor as mentioned above, 100 g of tetrahydrofuran, 5 g of acetic anhydride and 2 g of acetic acid were added. The temperature of the reactor was raised to 40° C. and reacted for 5 hours. After the completion of the reaction, the catalyst was removed from the mixture by filtration, and the unreacted tetrahydrofuran was recovered by reduced distillation. Polytetramethylene ether acetate with a number average molecular weight of 1223 and a Mw/Mn=1.98 was obtained. The yield is 58.2%.

Workup

  1. additionwere added
  2. customreacted for 5 hours
  3. customAfter the completion of the reaction
  4. customthe catalyst was removed from the mixture by filtration
  5. distillationthe unreacted tetrahydrofuran was recovered by reduced distillation

Sources & evidence

ORD record
ord-a7efaf958081486290515ac9adde7e93
Source dataset
uspto-grants-1994_09
Patent number
US05344964

Reaction notes

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