Acetic Anhydride → Ether acetate

HRID 2225951Notes

Reaction equation

HRID 2225951 reaction equation
[O:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:6]([O:9]C(=O)C)(=[O:8])[CH3:7]>C(O)(=O)C>[CH3:3][CH2:2][O:1][CH2:5][CH3:4].[C:6]([O-:9])(=[O:8])[CH3:7]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 8028Tetrahydrofuran

Product 1

HCID 21226428Ether acetateYield 29%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
50 °C

Procedure

The obtained catalyst was pulverized into 40-80 mesh. 15 g of the pulverized catalyst was placed in a slurry reactor as mentioned above, 100 g of tetrahydrofuran, 3 g of acetic anhydride and 1 g of acetic acid were added. The temperature of the reactor was raised to 50° C. and reacted for 90 minutes. After the completion of the reaction, the catalyst was removed from the mixture by filtration, and the unreacted tetrahydrofuran was recovered by reduced distillation. Polytetramethylene ether acetate with a number average molecular weight of 1927 and a Mw/Mn=1.89 was obtained. The yield was 29%.

Workup

  1. additionwere added
  2. customreacted for 90 minutes
  3. customAfter the completion of the reaction
  4. customthe catalyst was removed from the mixture by filtration
  5. distillationthe unreacted tetrahydrofuran was recovered by reduced distillation

Sources & evidence

ORD record
ord-dcc49eb70a6843f285ead2c255c6908c
Source dataset
uspto-grants-1994_09
Patent number
US05344964

Reaction notes

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