HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 2-(2-Hydroxyethyl)-pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | 2-Methylpyrazine | HCID 7976 | — |
| Product | 2-(2-Hydroxyethyl)-pyrazine | HCID 522247 | 32% |
Reaction Steps
A mixture of 90.0 g (956 mmol) of 2-methylpyrazine and 6.4 g (212 mmol) of paraformaldehyde was heated in a stainless steel autoclave at 165° C. for 5 hours, The residue was distilled under iced aspirator pressure (ca. 10 mmHg) to yield 8.28 g (32%) of a light pink oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05344830 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-9ae351cf1bac4f44b92cbc37972c8a16 |
| Source note | uspto-grants-1994_09 |