Phthalimide → Potassium phthalimide

HRID 2226248Notes

Reaction equation

HRID 2226248 reaction equation
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[OH-].[K+:13]>C(O)C>[CH:9]1[CH:10]=[C:2]2[C:1]([N-:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=1)=[O:11].[K+:13]

Participants

4

Reactant 2

HCID 6809PhthalimideHCID 14797Potassium Hydroxide

Product 1

HCID 3356745Potassium phthalimide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
0 °C

Procedure

In a 1-liter three-neck round bottom flask, phthalimide (50 g) was suspended in ethyl alcohol (500 ml) and cooled to about 0° C. under stirring. A solution of alcoholic KOH (19 gm in 150 ml alcohol) was added slowly over a period of 15-20 mins., while keeping the mass temperature at 0°-5° C. After the addition was complete, the reaction mixture was stirred for 1/2 hour at 0°-5° C. and then filtered.

Workup

  1. customat 0°-5° C
  2. additionAfter the addition
  3. stirringthe reaction mixture was stirred for 1/2 hour at 0°-5° C.
  4. filtrationfiltered

Sources & evidence

ORD record
ord-87592add7d0947de8f3af6fcd031c7f3
Source dataset
uspto-grants-1994_09
Patent number
US05347000

Reaction notes

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