Hydrochloric Acid → GK-128

Participants

Reaction Steps

0.1 g of 2-[(2-methyl-1-imidazolyl)methyl]- 1H-naphtho[2,1-b]thiopyran-1-one obtained in Example 3, after dissolving in methanol, was converted into the hydrochloride with conc. hydrochloric acid. After evaporation of the solvent under reduced pressure, the residue was recrystallized from methanol - diethyl ether to give 64 mg of the title compound.

Provenance & Evidence