Sodium cyanoborohydride → HCID 67852668, compound

HRID 2226392Notes

Reaction equation

HRID 2226392 reaction equation
[NH2:1][C@H:2]([C:4]([N:6]1[CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8][C@H:7]1[C:15]([OH:17])=[O:16])=[O:5])[CH3:3].[NH:18]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:20]([CH2:27][C:28](=O)[C:29]([O:31][CH2:32][CH3:33])=[O:30])=[CH:19]1.C([BH3-])#N.[Na+]>>[C:29]([CH:28]([NH:1][C@H:2]([C:4]([N:6]1[CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8][C@H:7]1[C:15]([OH:17])=[O:16])=[O:5])[CH3:3])[CH2:27][C:20]1[C:21]2[C:26](=[CH:25][CH:24]=[CH:23][CH:22]=2)[NH:18][CH:19]=1)([O:31][CH2:32][CH3:33])=[O:30]

Participants

4

Reactant 3

HCID 5003444Sodium cyanoborohydrideHCID 12457675HCID 12457675, compoundHCID 13146116HCID 13146116, compound

Product 1

HCID 67852668HCID 67852668, compound

Procedure

As described in Example 1, react 1-[(S)-alanyl]octahydroindole-2(S)-carboxylic acid and ethyl indole-3-pyruvate with sodium cyanoborohydride to obtain the title compound.

Sources & evidence

ORD record
ord-4d7991b1065d4c61aa6f66c6ff8ec353
Source dataset
uspto-grants-1994_09
Patent number
US05348944

Reaction notes

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