2-Oxoglutaric Acid → HCID 67852469, compound

HRID 2226397Notes

Reaction equation

HRID 2226397 reaction equation
[NH2:1][C@H:2]([C:4]([N:6]1[CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8][C@H:7]1[C:15]([OH:17])=[O:16])=[O:5])[CH3:3].O=[C:19]([CH2:23][CH2:24][C:25]([OH:27])=[O:26])[C:20]([OH:22])=[O:21].C([BH3-])#N.[Na+]>>[C:20]([CH:19]([NH:1][C@H:2]([C:4]([N:6]1[CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8][C@H:7]1[C:15]([OH:17])=[O:16])=[O:5])[CH3:3])[CH2:23][CH2:24][C:25]([OH:27])=[O:26])([OH:22])=[O:21]

Participants

4

Reactant 3

HCID 512-Oxoglutaric AcidHCID 5003444Sodium cyanoborohydrideHCID 13146116HCID 13146116, compound

Product 1

HCID 67852469HCID 67852469, compound

Procedure

As described in Example 5, treat 1-[(S)-alanyl]octahydroindole-2(S)-carboxylic acid (prepared as described in Example 1) and 2-oxoglutaric acid with sodium cyanoborohydride to isolate the title compound.

Sources & evidence

ORD record
ord-ec48efa63a664a24b3fa99deba765b65
Source dataset
uspto-grants-1994_09
Patent number
US05348944

Reaction notes

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