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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2226421Generated: October 29, 2026

1-[N-benzyloxycarbonyl-(S)-alanyl]hexhydrofuro[3,4-b]pyrrole-2(S)-carboxylic acid → 1-[(S)-alanyl]hexahydrofuro[3,4-b]pyrrole-2(S)-carboxylic acid

https://huagongshe.com/reaction/2226421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[N-benzyloxycarbonyl-(S)-alanyl]hexhydrofuro[3,4-b]pyrrole-2(S)-carboxylic acidHCID 18654884—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product1-[(S)-alanyl]hexahydrofuro[3,4-b]pyrrole-2(S)-carboxylic acidHCID 18654890—

Reaction Steps

Dissolve 1-[N-benzyloxycarbonyl-(S)-alanyl]hexhydrofuro[3,4-b]pyrrole-2(S)-carboxylic acid in methanol. Add 10% palladium-on-charcoal and hydrogenate the mixture at atmospheric pressure. Filter the mixture and concentrate in vacuo to give 1-[(S)-alanyl]hexahydrofuro[3,4-b]pyrrole-2(S)-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05348944
Source datasetuspto-grants-1994_09
ORD IDord-40d263f00cae47d9abf168bf7bf0d4ca
Source noteuspto-grants-1994_09