Sodium Hydroxide → Bicyclo[4.2.0]octa-1,3,5-trien-2-ylmethanol

HRID 2226677Notes

Reaction equation

HRID 2226677 reaction equation
[CH:1]([C:3]1[CH:10]=[CH:9][CH:8]=[C:5]2[CH2:6][CH2:7][C:4]=12)=[O:2].[BH4-].[Na+].[OH-].[Na+]>O>[OH:2][CH2:1][C:3]1[CH:10]=[CH:9][CH:8]=[C:5]2[CH2:6][CH2:7][C:4]=12

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 4311764Sodium borohydrideHCID 10855492HCID 10855492, compound

Product 1

HCID 129361362Bicyclo[4.2.0]octa-1,3,5-trien-2-ylmethanol

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4-Formylbenzocyclobutene is reduced with sodium borohydride in water, containing 1% by weight of sodium hydroxide. 4-Hydroxymethylbenzocyclobutene is obtained.

Sources & evidence

ORD record
ord-20aabb22df994fb1afd81c62239192d4
Source dataset
uspto-grants-1994_09
Patent number
US05349095

Reaction notes

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