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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2226677Generated: October 31, 2026

Sodium Hydroxide → Bicyclo[4.2.0]octa-1,3,5-trien-2-ylmethanol

https://huagongshe.com/reaction/2226677

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantSodium borohydrideHCID 4311764—
ReactantHCID 10855492HCID 10855492—
SolventWaterHCID 962—
ProductBicyclo[4.2.0]octa-1,3,5-trien-2-ylmethanolHCID 129361362—

Reaction Steps

4-Formylbenzocyclobutene is reduced with sodium borohydride in water, containing 1% by weight of sodium hydroxide. 4-Hydroxymethylbenzocyclobutene is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05349095
Source datasetuspto-grants-1994_09
ORD IDord-20aabb22df994fb1afd81c62239192d4
Source noteuspto-grants-1994_09