HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-(2,5-dioxo-1-pyrrolidinyl) ester, (2S)- → HCID 178451949, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-(2,5-dioxo-1-pyrrolidinyl) ester, (2S)- | HCID 853883 | — |
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | Boc-Arg(NO2)-Gly-NH2 | HCID 178454199 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178451949 | HCID 178451949 | — |
Reaction Steps
The desired compound was prepared from 6.0 g of Boc-Arg(NO2)-Gly-NH2, 40 ml of 4 N HCl-AcOEt, 3.4 ml of Et3N and 5.1 g of Boc-Pro-OSu in the same manner as in Example 26-(4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05349050 |
| Source dataset | uspto-grants-1994_09 |
| ORD ID | ord-73b6f4aab7f74b0cba0d1a0bc1480753 |
| Source note | uspto-grants-1994_09 |