Methylparaben → HCID 18963625, compound

Participants

Reaction Steps

5.2 g of 8-bromooctene, 5.0 g of methyl 4-hydroxybenzoate and 14 g of potassium carbonate were added to 70 ml of 2-butanone, and the mixture was refluxed for 7 hours in an atmosphere of argon. After the solid matters formed therein were filtered off, the solvent was distilled off under reduced pressure. The residue was purified by a silica gel column chromatography, to obtain 4.9 g of compound (8) (Yield: 68%)

Provenance & Evidence