反应详情

Prepared from methyl 3-amino-5-(methylthio)-benzo[b]thiophene-2-carboxylate by alkylation with formaldehyde as described in the preparation of methyl 4-chloro-3-(dimethylamino)benzo[b]thiophene-2-carboxylate. Yield 71% after recrystallization from ether-petroleum ether; mp=63°-66° C.

1. customYield 71% after recrystallization from ether-petroleum ether