Isopropylamine → HCID 18963764, compound

Participants

Reaction Steps

Isopropyl amine (379 μL, 4.45 mmol) is added to a room temperature solution of 5-methoxy-(3-(1-methylethoxy))benzo[b]thiophene-2-carboxamide-1-oxide (250 mg, 0.89 mmol) in 25 mL of acetonitrile. Stirring is continued for 16 hours. The reaction mixture is concentrated and recrystallized from acetonitrile to provide 5-methoxy-3-[(1-methylethyl)amino]benzo[b]thiophene-2-carboxamide-1-oxide in 64% yield; mp=193.5°-194.5° C.

Provenance & Evidence