HCID 12571954, compound → HCID 12455099, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 660 mg (3.1 mmol) of N-acetyl-2-(acetylthio)-3-thiophenamine in 8 ml of toluene was degased in a pyrex tube under high vacuum. The tube was subsequently sealed under high vacuum and heated at 205° C. for 5 hr. Chromatographic separation on silica gel using hexane/EtOAc=5:1 gave 440 mg (80%) of product. 1H NMR (CDCl3) 7.40(s, 2H), 2.82(s, 3H)

Provenance & Evidence