1,3-Benzodioxole-5-ethanamine → HCID 18473365, compound

HRID 2227291Notes

Reaction equation

HRID 2227291 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[CH2:17]1[O:28][C:27]2[CH:26]=[CH:25][C:21]([CH2:22][CH2:23][NH2:24])=[CH:20][C:19]=2[O:18]1>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:24][CH2:23][CH2:22][C:21]2[CH:25]=[CH:26][C:27]3[O:28][CH2:17][O:18][C:19]=3[CH:20]=2)[N:3]=1

Participants

4

Reactant 2

HCID 738741,3-Benzodioxole-5-ethanamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 18473365HCID 18473365, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[2-(3,4-methylenedioxyphenyl)ethylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 3,4-methylenedioxyphenethylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-c354c13bd8204e6a84ceae0a6f2b6ce5
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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