2,6-dichloro-9-cyclopentyl-9H-purine → HCID 18473403, compound

HRID 2227294Notes

Reaction equation

HRID 2227294 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[CH2:17]([NH:19][C:20]1[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=1)[CH3:18]>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([N:19]([C:20]2[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=2)[CH2:17][CH3:18])[N:3]=1

Participants

4

Reactant 2

HCID 108011162,6-dichloro-9-cyclopentyl-9H-purineHCID 11804744N-ethylpyridin-3-amine

Product 1

HCID 18473403HCID 18473403, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[(3-pyridyl)-2-ethylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 3-(ethylamino)pyridine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-de1383cae74b4db9ba489bcd0be8bda2
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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