Benzenemethanamine, 3,4-dichloro- → HCID 18473383, compound

HRID 2227297Notes

Reaction equation

HRID 2227297 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[Cl:17][C:18]1[CH:19]=[C:20]([CH:23]=[CH:24][C:25]=1[Cl:26])[CH2:21][NH2:22]>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:22][CH2:21][C:20]2[CH:23]=[CH:24][C:25]([Cl:26])=[C:18]([Cl:17])[CH:19]=2)[N:3]=1

Participants

4

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 18473383HCID 18473383, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[(3,4-dichlorobenzyl)amino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 3,4-dichlorobenzylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-230105d657d94bd8be4217c0b09a3e1f
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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