Benzenemethanamine, 3-chloro- → HCID 53793598, compound

HRID 2227303Notes

Reaction equation

HRID 2227303 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]([CH3:13])[CH3:12])=[C:4](Cl)[N:3]=1.[Cl:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH2:19][NH2:20]>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]([CH3:13])[CH3:12])=[C:4]([NH:20][CH2:19][C:18]2[CH:21]=[CH:22][CH:23]=[C:16]([Cl:15])[CH:17]=2)[N:3]=1

Participants

4

Reactant 2

HCID 77802Benzenemethanamine, 3-chloro-HCID 112184902,6-dichloro-9-(propan-2-yl)-9H-purine

Product 1

HCID 53793598HCID 53793598, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[(3-chloro)benzylamino]-9-(2-propyl)purine is prepared from 2,6-dichloro-9-(2-propyl)purine, 3-chlorobenzylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-1f31f05bc3b743e4bf308c93a9568b99
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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