Triethylamine → HCID 18473312, compound

HRID 2227306Notes

Reaction equation

HRID 2227306 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.CN[C:19]1[NH:20][C:21]2[CH:27]=[CH:26][CH:25]=[CH:24][C:22]=2[N:23]=1.[CH2:28]([N:30](CC)CC)C>>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:30][CH2:28][C:19]2[NH:23][C:22]3[CH:24]=[CH:25][CH:26]=[CH:27][C:21]=3[N:20]=2)[N:3]=1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 676520N-Methyl-1H-benzo[d]imidazol-2-amineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 18473312HCID 18473312, compound

Procedure

2-Chloro-6-[(2-benzimidazolyl)methylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 2-(methylamino)benzimidazole, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-bb9bef37d7ee427fab416bb3b6164624
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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